When Tianna Moon lost three stone on Mounjaro, it seemed like everything was going right. But while she wanted her waist to shrink, she never expected the weight loss medication to make her breasts bigger.
The 30-year-old had ‘always’ had a larger chest, but after deciding in May 2024 that she wanted to lose some weight, her breast size ballooned from an L cup to an M. This means that her bust’s circumference grew by around an inch.
While the content creator from the UK thought it was ‘odd’ that her breasts were growing while her weight was shrinking, it wasn’t until she looked at online health forums and researched using ChatGPT that she realized something was wrong.
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Now diagnosed with gigantomastia, a rare condition that causes a rapid and extreme growth in breast tissue, Moon has seen her chest size increase further and now struggles to find any bras that can support her.
But Moon, who suffers serious back pain and sores as a result of her condition, says she has found ways to ‘make it work’, buying the biggest size of bra possible and squeezing into it.
However, this has caused painful cuts and tears under her breasts, which grew to 34NN as she lost a further two stone. She explained: “Bras are impossible. Bras in my size NN don’t exist.
“I decided to lose weight and eventually started on Mounjaro and lost three stone over the course of a year. In that time my breasts grew from an L cup to an M cup. »
She has since ‘stepped away’ from bras entirely as a result of the pain they cause, deciding that she is ‘happier without them’. But more than half a year after her July 2025 diagnosis, she is still struggling with her expanded bust.
“The side effects are like having numb arms quite a lot and having quite severe indentations on my shoulders, » Moon shared. « I have some light scarring under my breasts where bras have rubbed and ripped the skin open.
“Also laying on my back is not something I can do for a long period of time as it restricts the amount of air flow I can get in”.
After suffering a head injury in 2021 and becoming unemployed, Moon decided to join OnlyFans to earn some money from the extra attention that her then-size L chest got from strangers.
Moon said: “It got to the point where last September I was in Amsterdam for the Xbiz awards as I was nominated. I was walking around with another lady and she said, ‘don’t you realise those people are pointing at you and trying to get your attention?’
“It’s become so normal to me I don’t notice it anymore”.
But when she dropped from 19st to 14st and her chest size went up by three cup sizes, Moon decided to look into what could be causing this severe change. Having heard about a less drastic breast tissue growth condition, she decided to speak to her doctor.
She said: “Originally, he was looking at macromastia, but when I broke down medical history, the weight loss on Mounjaro and the increased growth and side effects, he was point-blank like ‘this is gigantomastia’.
“I got the diagnosis quite early because of the growth not being common with anything else. At that point, I decided to get rid of the extra weight and protect my back because of the diagnosis. »
Her breasts now collectively weigh around three stone, causing her daily pain. In November, Moon took further preventative steps to protect her health, paying to get a gastric sleeve fitted to prevent even more extreme back pain in the future.
But while she is considering breast reduction surgery, the OnlyFans creator has been raking in the cash since developing gigantomastia, earning around $13,000 per month.
She said: “I might as well try and reap the benefits of my medical condition rather than the negatives. »
And it was actually one of her fans who first noticed that her chest was expanding. She added: “As they got bigger, it was actually a subscriber who said you need to get remeasured because you are not the size say you are. »
Jeremy Clarkson reveals he was caught out with an unexpected side effect of Mounjaro while in the airport.
An estimated one in eight adults, a staggering 12 percent of the US population, have turned to the ‘fat loss’ jabs in a bid to shift some stubborn pounds.
These GLP-1 drugs work by mimicking a natural hormone which regulates blood sugar levels and makes users feel fuller for longer.
It means users have a reduced need to eat, and as a result can enjoy some significant weight loss.
Although the purpose of the medication is to treat type 2 diabetes, with Ozempic not technically approved by the FDA for weight loss, it hasn’t stopped people including the rich and famous from using them.
British TV presenter and Top Gear star, Clarkson, is apparently one of the latest celebs to have confessed to using the jabs – as he revealed he suffered quite an embarrassing blunder at airport security as a result.
The 65-year-old said in a post on X, formerly Twitter, he had a ‘Mounjaro problem’ he ‘never saw coming.’
« At airports you’re made to remove your belt and then told to stand in the body scanner with your arms in the air, » Clarkson penned.
This is apparently a problem as he said the situation means ‘you can’t hold your trousers up.’
The Clarkson’s Farm documentary maker appeared to joke about having lost a significant amount of weight on the drug, so much so that his trousers no longer fit and, presumably, dropped to the floor when he was scanned at airport security.
His hilarious blunder comes as scientists recently put the top three blockbuster jabs, Mounjaro, semaglutide (in Wegovy and Ozempic) and Saxenda to the test, which ultimately crowned Mounjaro as the best of the bunch.
The results, published in the Cochrane Database of Systematic Reviews, determined tirzepatide (the active ingredient in Mounjaro) helped patients shift the most weight and crucially keep it off for longer when compared to rival GLP-1 medications.
Mounjaro patients lost an impressive 16 percent of their body weight in just 12 to 18 months on the drugs, according to the review, and were able to maintain their new physique the longest by up to 3.5 years.
Doctor Crystal Wyllie at ZAVA also says Mounjaro effects are likely to kick in as early as week two.
As for weight loss, she said it’s likely around the week four mark that users will experience a physical change in their physique – or at least the number on the scale has gone down.
According to ZAVA, patients lose an average of four per cent of their starting body weight on Mounjaro within the first month.
So, if you’re starting out on the drugs and are planning a trip any time soon, perhaps pack a spare pair of trousers so you don’t get caught out like Clarkson…
A woman has explained just how much happier she is now that she has lost weight, but admits there was one serious side effect of the weight loss medication she used that she wasn’t expecting.
Weight loss drugs have quickly become all the rage, with many using them after being prescribed by a health professional.
Being praised by celebrities and normal citizens alike, many have found themselves wishing their doctor would prescribe a GLP-1 drug to help them shed the pounds.
While there are many stories of people loving the results, there have also been instances where the reported side effects have proven to be rather detrimental.
British woman Shona has explained her experience after getting on weight loss medication Mounjaro.
She noted that she has loved the way she looks after just being on it for five months; however, she’s also issued a warning to others.
Writing in a Mail Online op-ed, she explained: “I’ve been on it since the beginning of February and have lost 17kg – the equivalent of around two pounds a week.
“While I was 78kg (12st 4lb) when I started, I’m now 61kg (9st 10lb) and in this respect I couldn’t be more delighted. I haven’t been this weight since before the birth of my fourth child, Dolly, in 2009.
“It has been 16 years of watching the scales ominously creeping upwards, during which time I have been through perimenopause and then menopause. And it has taken just five incredible months to lose it all again. I can’t explain how amazing that feels.”
She also highlighted the positive comments she has gotten from her friends and families. However, she says she feels like she has developed an eating disorder as a result of being on the weight loss drug.
Explaining that she made herself throw up after consuming a cinnamon pastry, noting that feelings of guilt kicked in.
She wrote: “The truth is unsettling and something I would never have predicted, but I can no longer ignore the darker side of what is happening to me.
“The fact is that using fat jabs has at the very least encouraged an unhealthy relationship with food, and at the very worst triggered an eating disorder. This is the Mounjaro mind game nobody talks about. I now see food as the enemy, something to be avoided at all cost.”
Shona also quoted doctor Tom Hildebrandt, who said he was seeing an increase in patients with eating disorders taking weight-loss drugs.
She quoted him as saying: “In some cases, a person’s brain may interpret such dramatic, sudden weight loss as starvation, making people more obsessive about food.
“People who are taking these new weight-loss drugs may then find themselves compelled to further limit how much food they eat, even when it endangers their health. »
In response, the maker of Mounjaro, Eli Lilly, told UNILAD: « Patient safety is Lilly’s top priority, and we actively engage in monitoring, evaluating, and reporting safety information for all our medicines.
« Mounjaro (tirzepatide) should only be used when prescribed and supervised by a licensed healthcare professional, and prescriptions should be fulfilled and supplied by registered pharmacies or providers.
« We encourage patients to consult their doctor or other healthcare professional to discuss any possible side effects they may be experiencing. »
The results of a massive study examining the health outcomes of people taking weight loss medications has found out what really happens to your body when you stop taking the injections.
These GLP-1 agonist injections, which include brand names like Wegovy and Mounjaro, have helped millions of people to lose a considerable amount of body mass, becoming an integral tool in the fight against obesity.
They work by mimicking the glucagon-like peptide 1 hormone that helps you to regulate when and how much you eat, taking away the desire to eat more than you need that makes it so hard for many people to follow a diet plan.
But Oxford University researchers, who created a study examining GLP-1 drugs and the medical results of 9,341 patients from 37 other studies, have found that this stunning weight loss might only be temporary.
Publishing their findings in the British Medical Journal, the researchers found that patients dropped about a fifth of their total weight during a typical 39-week course of treatment, which would be an incredible result for a normal weight loss program.
However, once patients stopped receiving their GLP-1 medications, they found that many would regain a considerable amount of weight without the hunger-regulating effects of the GLP-1 drugs.
Oxford researcher Dr Susan Jebb warned: « People buying these need to be aware of the risk of fast weight regain when the treatment ends. »
On average, patients would regain 0.8kg (1.7lbs) per months, meaning that they returned to their pre-jab weight in just a year and a half.
This is a much more rapid weight gain than people who follow a normal diet plan and discontinue, which saw a monthly gain of 0.1kg (0.22lbs).
This rapid weight gain was not a result of the GLP-1 injections, but rather a lack of behavioral change from patients receiving the drugs, a researcher explained.
Oxford’s Dr Sam West said: “These medicines are transforming obesity treatment and can achieve important weight loss. However, our research shows that people tend to regain weight rapidly after stopping – faster than we see with behavioural programs. »
While the research showed that many were rapidly regaining their lost weight, it did not mean that these new treatments are not effective.
He added: “This isn’t a failing of the medicines – it reflects the nature of obesity as a chronic, relapsing condition.
« It sounds a cautionary note for short-term use without a more comprehensive approach to long-term weight management, and highlights the importance of primary prevention.”
Other studies have indicated that these GLP-1 drugs can have a positive impact on a number of health metrics beside weight, with benefits for your brain and cardiovascular health.
But another finding of the study was that some of these observable health benefits also return to normal after a short period. Like with weight, they found that positive blood pressure and cholesterol biomarkers faded after 1.4 years.
Downsides to a popular diet known for its weight loss benefits have been revealed in a new study involving mice.
Weight loss is a lot of people’s goal when it comes to taking up a new diet and lifestyle. Whether it’s fasting, eating just one meal a day, or possibly challenging yourself not to eat after a certain time in the evening, people (myself included) will try just about anything to shift a few pounds.
One thing that’s been proven to be helpful when it comes to losing weight is the ketogenic (keto) diet.
According to Healthline, people can expect to lose anywhere between two and ten pounds in the first seven days of doing the difficult diet, as it shifts your body into ketosis (a natural metabolic state where the body burns fat for fuel instead of carbohydrates).
What is the keto diet?
The keto diet, created in 1921 to help manage epilepsy, consists of a person eating a high-fat and low-carb diet. Typically a person’s daily diet will be made up of 55-60 per cent fat, 30 to 35 per cent protein, and a maximum of 10 per cent carbs.
How many grams this works out to be depends on each individual’s calorie intake.
Downsides of the diet
In a new study published by University of Utah Health in October 2025, it was found that the keto diet can have a potentially dangerous impact on metabolic health, including how the body processes fats and carbs.
Researchers studied mice as part of the study and looked at the longer-term effects of the keto diet; one red flag being an increased risk of developing fatty liver disease.
Amandine Chaix, PhD, assistant professor of nutrition and integrative physiology at the university and senior author of the study, said of the findings: « One thing that’s very clear is that if you have a really high-fat diet, the lipids have to go somewhere, and they usually end up in the blood and the liver. »
Chaix added that the diet was ‘definitely not protective in the sense of fatty liver disease’.
The study also found that after two to three months on the keto diet, the mice had low levels of blood sugar and insulin because the diet harmed their blood sugar regulation.
« The problem is that when you then give these mice a little bit of carbs, their carb response is completely skewed, » Chaix said of this. « Their blood glucose goes really high for really long, and that’s quite dangerous. »
With the findings in mind, Molly Gallop, PhD, assistant professor of anatomy and physiology at Earlham College, who led the study, warned that people should speak to their doctors if they wish to go on a keto diet.
Benefits of the diet
There are so many benefits of the diet, however. As well as weight loss, previous research has suggested that the keto diet can also reduce seizures in children, says Harvard Health, and improve blood sugar levels in type 2 diabetes patients.
Also, there have been questions raised about the neuroprotective effects the diet has when it comes to brain disorders such as Parkinson’s, Alzheimer’s, multiple sclerosis, sleep disorders, autism, and even brain cancer.
